Expression of membrane hsp90 is a molecular signature of t cell activation

HIGHLIGHTS

• who: Scott A. Scarneo from the DepartmentDuke University have published the research work: Expression of membrane Hsp90 is a molecular signature of T cell activation, in the Journal: Scientific Reports Scientific Reports
• what: The authors report that mHsp90 expression is significantly upregulated in activated T_cell populations in response to stimulation.

SUMMARY

Regulation of mHsp90 chaperone machinery in T_cells. A hallmark of T_cell function is to proliferate rapidly in response to antigen presentation along with appropriate cytokine and costimulatory signaling. Hsp90 has been shown to be upregulated following T_cell immune or cytokine . . .

 



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