Clec5a and tlr2 are critical in sars-cov-2-induced net formation and lung inflammation

HIGHLIGHTS

  • who: Pei-Shan Sung from the (UNIVERSITY) have published the research: CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation, in the Journal: (JOURNAL)
  • what: This study shows that SARS-CoV-2-activated platelets produce EVs to enhance thromboinflamu2011 mation via CLEC5A and and highlight the importance of CLEC5A and as therapeutic targets to reduce the risk of ARDS in COVID-19 patients. The authors report that COVID-19 EVs express abundant markers of activated platelets, and induce NET formation via CLEC5A and TLR2. The authors demonstrated that platelets . . .

     

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