Exiting the tunnel of uncertainty: crystal soak to validated hit

HIGHLIGHTS

• who: Mathew P., Martin and Martin E., M. Noble from the Cancer Research UK Drug Discovery Unit, Newcastle University, Paul O`Gorman Building, Framlington Place have published the research work: Exiting the tunnel of uncertainty: crystal soak to validated hit, in the Journal: (JOURNAL)
• what: This approach complements work from the Cravatt laboratory, in which fragment screening is conducted within human cells (Parker et_al, 2017; Asiaban et_al, 2020).
• how: This article will provide an overview of some techniques and tools that can be used to inform this early hit-expansion phase. It must . . .
  

   

  

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