Assessing agreement between different polygenic risk scores in the uk biobank

HIGHLIGHTS

  • who: Lei Clifton from the University of have published the article: Assessing agreement between different polygenic risk scores in the UK Biobank, in the Journal: Scientific Reports Scientific Reports
  • what: This study has been conducted under the UK Biobank application ID 33952. For comparing different PRS, the authors focused on two aspects: firstly, the consistency of the selected SNPs and performance metrics. The authors focused on the top 1% of risk because of the widely-promulgated concept that these risks approximate those of the risks for monogenic u00adtraits4. The authors demonstrate that for three common . . .

     

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