Construction and validation of an immunoediting-based optimized neoantigen load (iotnl) model to predict the response and prognosis of immune checkpoint therapy in various cancers

HIGHLIGHTS

  • who: Xiaofan Su et al. from the Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi`an Jiaotong University, Xi`an, Shanxi, China have published the article: Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers, in the Journal: (JOURNAL)
  • how: The authors developed ioTNL model which indicates the immunoediting-based optimized tumor neoantigen load by identifying tumor clones that could induce immune elimination. The authors proposed a direction for improvement based on the neoantigen . . .

     

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