Alpha-synuclein strain variability in body-first and brain-first synucleinopathies

HIGHLIGHTS

  • who: Nathalie Van Den Berge from the Institute for Clinical Medicine, Aarhus University, Aarhus, Denmark, Nuclear Medicine and PET, Aarhus University Hospital have published the research work: Alpha-Synuclein Strain Variability in Body-First and Brain-First Synucleinopathies, in the Journal: (JOURNAL)
  • what: The model proposes two overall subtypes of PD: a brain-first type, where pathology initially appears in a single hemisphere in the brain (usually the amygdala or olfactory bulb). In the past decade, an increasing number of studies aim to model body-first LBD by initiating pathology in the gut (Pan-Montojo . . .

     

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