Bioinspired tetraamino-bisthiourea chiral macrocycles in catalyzing decarboxylative mannich reactions

HIGHLIGHTS

  • who: Hao Guo and collaborators from the Beijing National Laboratory for Molecular Sciences, CAS Key University of Chinese Academy of Sciences, Beijing, China have published the article: Bioinspired tetraamino-bisthiourea chiral macrocycles in catalyzing decarboxylative Mannich reactions, in the Journal: (JOURNAL)
  • what: To expand more applications, herein the authors report a systematic synthesis of tetraamino-bisthiourea chiral macrocycles and their performance in catalyzing the decarboxylative Mannich addition of malonic acid half thioesters (MAHTs) to isatin-derived ketimines.
  • how: The above results showed that the tetraamino-bisthiourea chiral macrocycles can efficiently catalyze the decarboxylative . . .

     

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