An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data

HIGHLIGHTS

• who: Xiao-Song Wang from the UPMC Hillman Cancer Center, University of have published the article: An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors propose a class of methods for big data-based precision medicine called integral genomic signature (iGenSig) analysis, which is designed to provide more robust clinical decision support with higher transparency and cross-dataset applicability (Fig 1). The authors propose that the redundancies within high-dimensional features can in fact overcome sequencing errors and bias especially . . .
  

   

  

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