Anti-trap/ssp2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-csp monoclonal antibodies

HIGHLIGHTS

• who: Brandon K. Wilder from the (UNIVERSITY) have published the paper: Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies, in the Journal: (JOURNAL)
• what: The authors show that the polyclonal antibody response to PyTRAP ectodomain can substantially reduce parasite infection of hepatocytes in_vitro.
• how: The resulting sensorgram data were evaluated using ForteBio Data Analysis software (version 7.0.1.5) to generate a fit to the 11 binding model and provide estimates for the kon and kdis rate constants (see sample sensorgrams and . . .
  

   

  

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