Comparative analysis of mesenchymal stem cells cultivated in serum free media

HIGHLIGHTS

SUMMARY

    At P5 and P10, ADCSs_FBS showed a significant increase in the formation frequency of MN, NBUDs, and NPB compared to ADSCs_SFM, which showed a significant decrease in all three variables, except that at P5, the NBP formation of ADSCs_SFM was not significantly different from ADSCs_FBS. A comparative multi‑omics analysis of ADSCs_FBS and ADSCs_SFM. About 11% and 16% of the proteins were up-regulated in ADSCs_SFM and ADSCs_FBS, respectively. Comparison of therapeutic efficacy of ADSCs_SFM and ADSCs_FBS in acute pancreatitis mouse model. Both enzymes decreased by about 29% and 33% after infusion of ADSCs_FBS . . .

     

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