HIGHLIGHTS
- who: Camilla Cristalli from the Tel Aviv University, Israel Italy have published the research: Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response, in the Journal: (JOURNAL)
- what: The authors evaluate the efficacy of MC3343, a new quinoline-based DNMTi with high activity against cancer cells, including osteosarcoma . Taken together, the authors demonstrate in this study that DNMT1 is essential for the proliferation and survival of EWS cells.
- how: The efficacy of MC3343 was tested in . . .
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