Efficacy, t cell activation and antibody responses in accelerated plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

HIGHLIGHTS

• who: Javier Ibanez from the Tu00dc, Stage-B study design This single-center, randomized, placebo-controlled, double-blinded phaseI/-II study was conducted from April , to December , at the Institute of Tropical Medicine in Tu00fcbingen, GermanyThe PfSPZ formulation team was unblinded and thus was not involved in clinical or diagnostic activities. Approval was obtained from the Ethics Committee of the Eberhard Karls University and University Clinics (EudraCT number, National Clinical Trial number (NCT): NCT02115516). The study was performed in accordance with Good Clinical Practice/International Conference on Harmonization guidelines. The sample size was calculated using the function . . .
  

   

  

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