HIGHLIGHTS
- who: Nadine Gehrke from the hit:, ) and Fas (logFC=063, p andlt have published the paper: Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure, in the Journal: (JOURNAL) of 11/05/2022
- what: The current analysis explored mice with a hepatocyte-specific overexpression of Bcl-3 in two models of experimental ALF in_vivo and in a hepatocyte-based ex vivo culture system. The authors show that Bcl-3 acts as a pro-survival factor in hepatocytes by a mechanism located upstream of the mitochondrial Cell Death and Disease 13 . . .
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