Treatment with methotrexate associated with lipid core nanoparticles prevents aortic dilation in a murine model of marfan syndrome

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  • who: Raul Cavalcante Maranhu00e3o from the Laboratory of Metabolism and Lipids, Heart Institute (InCor) of the Medical School Hospital, University of, Brazil have published the article: Treatment With Methotrexate Associated With Lipid Core Nanoparticles Prevents Aortic Dilation in a Murine Model of Marfan Syndrome, in the Journal: (JOURNAL)
  • what: In the current study, it was hypothesized whether precocious treatment with LDEMTX could prevent the development of dilation, dissection, and other aortic lesions that develop in the MFS murine model. Among the five murine models of MFS described in the literature, the current model has the . . .

     

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