The quest for anti-α-synuclein antibody specificity—lessons learnt from flow cytometry analysis

HIGHLIGHTS

• who: Iryna Prots from the Department of Stem Cell Biology, University, Friedrich-Alexander-Universitu00e4t Erlangen-Nu00fcrnberg, Friedrich-Alexander-Universitu00e4t Erlangen-Nu00fcrnberg, Germany have published the Article: The Quest for Anti-u03b1-Synuclein Antibody Specificityu2014Lessons Learnt From Flow Cytometry Analysis, in the Journal: (JOURNAL)
• what: Strikingly, the authors demonstrate a previously unobserved non-specificity of the LB509 antibody by successfully blocking it with other synucleins and tubulin. In the present study, three different anti-aSyn antibodies (2A7, LB509, and MJFR1) were compared for their sensitivity and specificity to stain aSyn using flow cytometry as a detection . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.