Three-dimensional wide-field fluorescence microscopy for transcranial mapping of cortical microcirculation

HIGHLIGHTS

• who: Quanyu Zhou from the (UNIVERSITY) have published the research: Three-dimensional wide-field fluorescence microscopy for transcranial mapping of cortical microcirculation, in the Journal: (JOURNAL) of 16/Dec/2022
• what: The authors demonstrate real-time volumetric mapping of the murine cortical microcirculation at capillary resolution without employing cranial windows, thus simultaneously delivering quantitative perfusion information across both brain hemispheres. The authors propose two possible implementations for astigmatism-based 3D wide-field fluorescence microscopy using either multifocal illumination (MI) or sparse localization (SL) of point emitters.
• how: This result is also in congruence . . .
  

   

  

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