Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model

HIGHLIGHTS

  • who: Harry L. Stannard from the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australiathe University have published the article: Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model, in the Journal: (JOURNAL) of 15/09/2022
  • what: In this study A(H1N1)pdm09 viruses with treatment-emergent dual-mutations (NA-H275Y and PA-I38T) were identified in two immunocompromised (undergoing cancer treatment) patients treated with OST or PER in combination with BXM. This study assessed the replicative capacity airborne transmissibility and relative fitness of such viruses . . .

     

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