Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis

HIGHLIGHTS

  • who: Michael Pudjihartono from the (UNIVERSITY) have published the Article: Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis, in the Journal: (JOURNAL)
  • what: The authors describe how advancements in sequencing technologies have led to the identification of a large number of mutations with uncharacterized biological significance. Identifying key cancer-associated germline and somatic variants has been the primary goal for many past and present cancer studies, putting together patterns of mutational signatures into clues that infer ideal treatment strategies.
  • future: This unprecedented . . .

     

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