HIGHLIGHTS
- who: Dorit Naot from the Department of Medicine, Faculty of Medical and Health Sciences, University have published the research: Factors secreted by monosodium urate crystal-stimulated macrophages promote a proinflammatory state in osteoblasts: a potential indirect mechanism of bone erosion in gout, in the Journal: (JOURNAL)
- what: The aim of this study was to determine the indirect macrophage-mediated effects of MSU crystals on osteoblasts. The study shows that soluble mediators secreted from macrophages in response to stimulation by MSU crystals affect gene_expression and secretion of factors from osteoblastic cells. The authors aimed to model . . .
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