Recent advances in mrna-lnp therapeutics: immunological and pharmacological aspects

HIGHLIGHTS

  • who: Seyed Hossein Kiaie from the School of Systems Biology, Laboratory of Molecular Virology, George Mason, , Blvd, USA have published the research: Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects, in the Journal: (JOURNAL)
  • what: This study reveals the interplay of immune responses with LNP compositions and characterization and clarifies the interaction of mRNA-LNP therapeutics with dendritic macrophages neutrophile cells and complement.
  • how: Similar observations were obtained in another study in which liposomes of either 250 or 980 nm in size were loaded with influenza A hemagglutinin .

SUMMARY . . .

 

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