HIGHLIGHTS
SUMMARY
Pterygium is regarded as a limbal stem_cell disorder with precancerous Frontiers in Endocrinology features. The differential gene_expression analysis The differential gene_expression analysis identified a total of 49 DEGs (|log2FC| >1 and p-value and amp;lt; 0.05) on primary pterygium samples vs. adjacent normal conjunctiva samples. EMT and myogenesis in the results represent epithelial_cells converted to myofibroblasts, serving as a key feature of pathological tissue repair and playing an essential role in pterygium progression. Among them, FOS and FOSB, as members of the AP-1 transcription factor complex, were upregulated in corneal epithelial_cell . . .
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