Human papillomavirus 42 drives digital papillary adenocarcinoma and elicits a germ-cell like program conserved in hpv-positive cancers

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    To Downloaded from http://aacrjournals.org/cancerdiscovery/article-pdf/doi/10.1158/2159-8290.CD-22-0489/3212195/cd-22-0489.pdf by guest on 26 February 2023 papillomavirus (HPV), Merkel cell carcinoma by Merkel cell polyomavirus (MCV), Kaposi validate the discovery of HPV42 in DPA, the authors enriched viral nucleic_acids from tumor samples using a hybridization-based sequence capture assay (ViroCap) and confirmed the presence of HPV42 RNA and DNA (Fig 1C, Supplementary Fig S1B and C, Supplementary Table S2 and S3). HPV42, previously classified as a non-oncogenic HPV, induces transformation in_vitro . . .

     

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