Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in ct26 tumor-bearing mice

HIGHLIGHTS

• who: Wararat Kittikulsuth from the DepartmentKagawa University have published the article: Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrated that VIP antagonist enhanced M1 markers TNF-u03b1, iNOS, and CXCL10, reduced Mrc-1 mRNA expression, and increased phagocytic ability against CT26 colon cancer cells in mouse macrophage RAW264.7 cells incubated with CT26-CM.
• how: The data indicated that these beneficial effects of VIP antagonist were likely mediated through the inhibition of . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.