(-)-epigallocatechin-3-gallate directly binds cyclophilin d: a potential mechanism for mitochondrial protection

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  • who: Annan Wu and collaborators from the College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China have published the research work: (-)-Epigallocatechin-3-gallate Directly Binds Cyclophilin D: A Potential Mechanism for Mitochondrial Protection, in the Journal: Molecules 2022, 8661 of /2022/
  • what: The authors found that EGCG to CypD and this interaction was investigated by surface plasmon resonance (SPR) nuclear magnetic resonance (NMR) and molecular dynamic (MD) simulation. In this study, a direct binding was identified for CypD and EGCG, a natural polyphenol compound form green tea. The authors demonstrate that . . .

     

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