HIGHLIGHTS
- who: James C. Murphy from the (UNIVERSITY) have published the article: Kaposiu2812s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs, in the Journal: (JOURNAL) of 25/03/2022
- what: The authors explore the possibility that KSHV manipulates ribosome biogenesis producing specialised ribosomes which preferentially translate viral transcripts. The authors demonstrate the enhanced association of ribosomal biogenesis factors BUD23 and NOC4L, and the KSHV ORF11 protein, with small ribosomal subunit precursor complexes during lytic replication.
- how: To validate the integrity of isolated PNO1 pre40S complexes the authors examined their rRNA . . .
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