Top2a expression in pheochromocytoma and abdominal paraganglioma: a marker of poor clinical outcome?

HIGHLIGHTS

• who: Karolina Solhuslu00f8kk Hu00f6se from the Department of Oncologyu2011Pathology, Karolinska Institutet, Stockholm, Sweden have published the article: TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?, in the Journal: (JOURNAL)
• what: The aim of this study was to investigate whether TOP2A could be used as a marker of poor clinical outcome in PPGL and distinguish metastatic tumors from non-metastatic ones.
• how: A recent effort using single cell sequencing data found that TOP2A and MKI67 mRNA levels were elevated in metastatic PPGLs with aberrancies in the tricarboxylic acid (TCA . . .
  

   

  

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