Structural basis for a conserved neutralization epitope on the receptor-binding domain of sars-cov-2

HIGHLIGHTS

  • who: Kuan-Ying A. Huang from the (UNIVERSITY) have published the paper: Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2, in the Journal: (JOURNAL) of 17/06/2022
  • what: The authors identified a cryptic and conserved epitope capable of eliciting broad anti-SARS-CoV-2 antibodies, represented by antibody IY-2A, which has not been reported previously.
  • how: The results showed that a relatively small percentage of convalescent and post-ChAdOx1 nCoV-19 (AZD1222)23 sera demonstrated competitive activity with EY-6A binding compared to . . .

     

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