Nrf-2/ho-1 pathway-mediated shox2 activation is a key switch for heart rate acceleration by yixin-fumai granules

HIGHLIGHTS

  • who: Heng Zhang and colleagues from the Liaoning University of Traditional Chinese Medicine, Shenyang, China have published the research work: NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules, in the Journal: Oxidative Medicine and Cellular Longevity 15 of 26/09/2022
  • what: The authors focused on YXFMs` regulation function in T-type calcium channels and explored its relationship with the NRF-2/HO-1 pathway and SHOX2.
  • how: In vitro experiment results indicated that ML385 si-SHOX2 LDN193189 and Mibefradil reversed . . .

     

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