Mir-489 confines uncontrolled estrogen signaling through a negative feedback mechanism and regulates tamoxifen resistance in breast cancer

HIGHLIGHTS

  • who: Mithil Soni and collaborators from the Department of Biological Science, University of South Carolina, Columbia, SC, USA have published the Article: miR-489 Confines Uncontrolled Estrogen Signaling through a Negative Feedback Mechanism and Regulates Tamoxifen Resistance in Breast Cancer, in the Journal: (JOURNAL) of 26/06/2022
  • what: The authors systematically investigated the functional roles of miR-489 in ER+ breast cancer.
  • how: 2.1. miR-489 Expression Is Lost in Tamoxifen Resistance Predicts Breast Cancer Aggressiveness and Is Regulated by the Estrogen/ERu03b1 Axis To specifically identify miRNAs that are clinically . . .

     

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