HIGHLIGHTS
SUMMARY
Despite this, a great effort is still needed to study the effects of contaminants in this species and its susceptibility to chemical insult not only on natural organisms but also by using in_vitro methodologies that can replace laboratory tests on living animals. To date, few studies have been published that apply in_vitro methodologies to C. caretta and other sea turtles, mostly Chelonia mydas. Ex vivo tissue_cultures allow to preserve, at least to an extent, tissue-ultrastructure and biochemical functions, thus offering a unique platform to investigate in_vitro tissue-cell responses to different exogenous insults . . .
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