Upregulated gprc5a disrupting the hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the camp-creb axis

HIGHLIGHTS

  • who: Weidan Fang from the The First Affiliated Hospital of University, Jiangxi Province, China Jiangxi Key Laboratory for Individualized have published the Article: Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis, in the Journal: (JOURNAL)
  • what: The authors show that the proliferation and migration induced by GPRC5A in could be rescued by inhibiting expression. The authors first address the roles of GPRC5A in nude mice and show that its overexpression in pancreatic cancer is predictive of poor prognosis. The authors demonstrate that GPRC5A . . .

     

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