Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: a biomarker of response to corticosteroids

HIGHLIGHTS

  • who: Jingya Yan from the Kids Neuroscience Centre, The Children`s Hospital at Westmead, Faculty of Medicine and Health, University of Sydney, NSW have published the article: Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids, in the Journal: (JOURNAL)
  • what: The authors aimed to explore the changes in CSF concentrations of metabolites in the tryptophan-kynurenine pathway using a LC-MS/MS method to compare children with epileptic spasms to controls, and explore associations with aetiology and response to treatment. The direct precursor-product ratio is commonly used to . . .

     

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