Radotinib attenuates tgfβ -mediated pulmonary fibrosis in vitro and in vivo: exploring the potential of drug repurposing

HIGHLIGHTS

• who: Suji Baek from the 3u2011gil, Dobongu2011gu, Seoul, Republic of Korea have published the paper: Radotinib attenuates TGFu03b2 -mediated pulmonary fibrosis in vitro and in vivo: exploring the potential of drug repurposing, in the Journal: (JOURNAL)
• what: The authors aimed to investigate whether (Rb) could inhibit pulmonary fibrosis by inhibiting TK in vitro and in vivo. The authors explored the antifibrosis effect of Rb in TGF-u03b21-stimulated A549 cells and in a bleomycin-induced rat model to provide basic data for the development of therapeutic agents through the significant inhibition of IPF. The authors . . .
  

   

  

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