HIGHLIGHTS
- who: Garrett W. Cooper and Andrew L. Hong from the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA have published the article: SMARCB1-Deficient Cancers: Novel Molecular Insights and Therapeutic Vulnerabilities, in the Journal: Cancers 2022, 14, 3645. of /2022/
- what: While this model demonstrates the potent tumor-suppressive function of SMARCB1, the resulting lymphomas do not offer a faithful model for most human SMARCB1-deficient cancers.
- future: Studies are needed to validate these mechanisms but current studies offer promising new insights that may be used for future therapeutics . Studies . . .
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