HIGHLIGHTS
- who: Jing Xia from the Department of Pediatric Laboratory, The Affiliated Wuxi Children`s Hospital of Nanjing Medical University, Wuxi, Jiangsu, China have published the paper: GSK3 inhibitor suppresses cell growth and metabolic process in FLT3-ITD leukemia cells, in the Journal: (JOURNAL)
- what: Findings from this study provide valuable insights into the treatment of AML patients. The authors demonstrated that low concentration of GSK3u03b2 inhibitor, BIO, suppressed the proliferation of FLT3-ITD mutated cells by elevating cyclin D2 expression, reducing p21 expression, inhibiting DNA_polymerase and eventually causing G1 cell cycle arrest.
- how . . .
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