Hdac1 disrupts the tricarboxylic acid (tca) cycle through the deacetylation of nur77 and promotes inflammation in ischemia-reperfusion mice

HIGHLIGHTS

  • who: Zhenhua Wu from the (UNIVERSITY) have published the Article: HDAC1 disrupts the tricarboxylic acid (TCA) cycle through the deacetylation of Nur77 and promotes inflammation in ischemia-reperfusion mice, in the Journal: (JOURNAL)
  • what: In this study, in_vivo mouse models of myocardial I/R and a hypoxia/ regeneration (H/R) injury model in Raw264.7 cells were designed to investigate the role of HDAC1 during myocardial injury.
  • how: The authors developed an I/R mouse and H/R injury model in RAW264.3 cells to demonstrate that I/R-induced myocardial injury can . . .

     

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