Network pharmacology and molecular docking technology-based predictive study of the active ingredients and potential targets of rhubarb for the treatment of diabetic nephropathy

HIGHLIGHTS

  • who: Shaojie Fu from the Department of Nephrology, the First Hospital of Jilin University, Changchun, Jilin, China have published the paper: Network pharmacology and molecular docking technology-based predictive study of the active ingredients and potential targets of rhubarb for the treatment of diabetic nephropathy, in the Journal: (JOURNAL)
  • what: We used network pharmacology analysis and molecular docking technology to explore the potential mechanism of the effects of rhubarb against DN, clarifying the core active ingredients in rhubarb were rhein, beta-sitosterol and aloe-emodin, and the key therapeutic targets were TP53, CASP8, CASP3, MYC . . .

     

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