Molecular classification and overcoming therapy resistance for acute myeloid leukemia with adverse genetic factors

HIGHLIGHTS

  • who: Daisuke Ikeda and colleagues from the Department of Hematology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan have published the paper: Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors, in the Journal: (JOURNAL)
  • what: The authors focus on the biological background and real-world etiology of these adverse genetic factors and then describe a strategy to overcome the clinical disadvantages in terms of targeting pivotal molecular mechanisms. The ad hoc analysis of the AML201 study focused 8 of 22 on 197 patients in which comprehensive genetic data were . . .

     

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