HIGHLIGHTS
SUMMARY
The work focused on comparing the cellular effects of Rigvir to other echovirus 7 isolates, because originally Rigvir is also an echovirus 7 isolate. The authors used the genome sequences made by the authors and others to put Rigvir on a phylogenetic_map of echovirus 7 isolates. In his comments, Dr. Alberts aims to clarify the actual state of Rigvir as a potential oncolytic virus in clinical use from company perspective. He claimed that the data ignore previous cellular results, but in fact, previous cellular studies prompted the authors to perform the current study. By . . .
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