Hax-1 regulates radiation-induced mitochondrial-dependent apoptosis of uveal melanoma cells through pi3k/akt/ enos pathway

HIGHLIGHTS

• who: Sha Wang and colleagues from the Eye Center of Xiangya Hospital, Central South University, Xiangya Road, Changsha, China , have published the Article: Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/ eNOS Pathway, in the Journal: Journal of Oncology of 13/05/2022
• what: This research shows for the first time that HAX-1 triggers uveal melanoma cell apoptosis via mitochondria dependence via the stimulation of PI3K/AKT/ eNOS signal path and favorable modulation of Bax, Caspase 3, and Bcl2.
• how: The following two haX-1 . . .
  

   

  

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