Dyt-prkra mutation p222l enhances pact’s stimulatory activity on type i interferon induction

HIGHLIGHTS

• who: Lauren S. Vaughn et al. from the Department of Biological Sciences, University of South Carolina, Sumter Street, Columbia, SC, USA have published the article: DYT-PRKRA Mutation P222L Enhances PACTu2019s Stimulatory Activity on Type I Interferon Induction, in the Journal: Biomolecules 2022, 713 of 17/05/2022
• what: The authors evaluate if the most prevalent substitution reported in patients alters functional role in of IFNs via the retinoic acid-inducible gene signaling. PACT`s functional role in the type I IFN induction in response to dsRNA is the focus of this study. The authors . . .
  

   

  

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