HIGHLIGHTS
- who: Michael D. Thompson from the DivisionUniversity School of Medicine, StLouis, MO, USA have published the research: Maternal obesogenic diet enhances cholestatic liver disease in offspring, in the Journal: Nutrition,
- what: Shifts in offspring microbiome after maternal obesogenic diet exposure drives increased cholestatic liver injury One mode of transmission of developmentally programmed phenotypes is for a dam to confer an altered microbiome to offspring, and the authors demonstrate that the gut microbiome in HF/HS offspring is sufficient to worsen cholestatic liver injury.
- future: Future studies evaluating specific taxa will be necessary to . . .
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