Nlrp3 inflammasome negatively regulates rankl-induced osteoclastogenesis of mouse bone marrow macrophages but positively regulates it in the presence of lipopolysaccharides

HIGHLIGHTS

• who: Mohammad Ibtehaz Alam and collaborators from the Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical have published the research work: NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides, in the Journal: (JOURNAL) of 28/03/2022
• what: For this study, the authors generated osteoclasts from BMMs under the presence or absence of NLRP3 inflammasome inhibitors to investigate the role of the NLRP3 inflammasome in osteoclastogenesis under physiological and infectious conditions. The authors the authors demonstrated how thethe NLRP3 . . .
  

   

  

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