Treatment strategies for non-small cell lung cancer harboring common and uncommon egfr mutations: drug sensitivity based on exon classification, and structure-function analysis

HIGHLIGHTS

  • who: Rui Kitadai and Yusuke Okuma from the Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan have published the research: Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis, in the Journal: Cancers 2022, 2519 of /2022/
  • what: An open-label phase 3 study was conducted to compare osimertinib 4 of 18 with platinum-based chemotherapy in advanced T790M-positive NSCLC patients who exhibited disease progression after first-line EGFR-TKI therapy. The analysis showed an improved OS . . .

     

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