Harmine, an inhibitor of the type iii secretion system of salmonella enterica serovar typhimurium

HIGHLIGHTS

• who: Yunjia Shi from the Harvard Medical School, United States Uppsala University, Sweden have published the Article: Harmine, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium, in the Journal: (JOURNAL)
• what: Harmine inhibited T3SS functions by reducing the transcription and expression of the T3SS regulatory_gene hilA and ultimately inhibited the invasion of S. Typhimurium in_vitro and reduces tissue damage in S. Typhimurium-infected mice in_vivo.
• how: All PCR experiments were analyzed in three replicates. The results showed that harmine inhibited SipA-TEM translocation into HeLa cells at 32 . . .
  

   

  

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