Dual coating of chitosan and albumin negates the protein corona-induced reduced vascular adhesion of targeted plga microparticles in human blood

HIGHLIGHTS

• who: Genesis Lopez-Cazares and Omolola Eniola-Adefeso from the Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA have published the research: Dual Coating of Chitosan and Albumin Negates the Protein Corona-Induced Reduced Vascular Adhesion of Targeted PLGA Microparticles in Human Blood, in the Journal: Pharmaceutics 2022, 1018 of /2022/
• what: In this work, alternate surface coatings for PLGA VTCs were explored for improved vascular wall adhesive interactions under human blood flow conditions-specifically, chitosan (CS) and human serum albumin (HSA). The authors explored the use of chitosan (CS) or albumin (typically from . . .
  

   

  

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