Plant alkaloid tetrandrine is a nuclear receptor 4a1 antagonist and inhibits panc-1 cell growth in vitro and in vivo

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  • who: Hyo-Seon Lee and colleagues from the Department of Food Science and Technology, Keimyung University, Daegu, Korea have published the research: Plant Alkaloid Tetrandrine Is a Nuclear Receptor 4A1 Antagonist and Inhibits Panc-1 Cell Growth In Vitro and In Vivo, in the Journal: (JOURNAL) of 14/08/2021
  • what: The orphan 4A1 (NR4A1) highly expressed human pancreatic cancer cells and exerts pro-oncogenic activity. previous study the authors demonstrated that fangchinoline (FCN) natural inhibitor of NR4A1 induces NR4A1-dependent apoptosis human pancreatic cancer cells. this study the authors evaluated FCN and its structural . . .

     

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