High-metastatic melanoma cells promote the metastatic capability of low-metastatic melanoma cells via exosomal transfer of mir-411-5p

HIGHLIGHTS

  • who: Hao Chen from the Alfonso el Sabio University, Spain have published the research work: High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p, in the Journal: (JOURNAL)
  • what: The authors show that exosomal crosstalk between metastatic POL and OL cells is a new mechanism of cancer metastasis. Since the authors are searching for POL-EXO miRNAs that promotes cancer metastasis, the authors focused on the 27 exosomal miRNAs that had more than 1-fold higher expression in POL-EXO compared to OL-EXO . . .

     

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