HIGHLIGHTS
SUMMARY
At deep timescales where genes and genomes are highly diverged, copies of marker genes which tend to be conserved across many species are identified in the genomes being studied. A marker gene is defined as a protein-coding gene which ideally occurs as a single-copy gene in every studied genome. While early phylogenetic studies relied on one or two marker genes such as SSU rRNA, the advance of sequencing technologies including next generation sequencing and more recently single molecule real time sequencing has enabled the transition to phylogenomics and the construction of datasets . . .
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