Low-grade inflammation in the pathogenesis of osteoarthritis: cellular and molecular mechanisms and strategies for future therapeutic intervention

HIGHLIGHTS

• who: M Alaa Terkawi and collaborators from the Department of Orthopedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University have published the research: Low-Grade Inflammation in the Pathogenesis of Osteoarthritis: Cellular and Molecular Mechanisms and Strategies for Future Therapeutic Intervention, in the Journal: Biomedicines 2022, 10, 1109. of /2022/

SUMMARY

Osteoarthritis (OA), the most prevalent form of arthritis, affects 25% of the world`s population, especially those between 55 to 70. In OA, inappropriate biomechanical and biochemical signals in chondrocytes impair their regulated metabolic activities and shift to catabolic . . .

 



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